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Drug Discovery 2010

In 2010 the Drug Discovery Symposium will encompass eight scientific sessions.

  1. Ion Channel Drug Discovery
  2. Strategies to Reduce Candidate Attrition
  3. Cells and Proteins for Drug Discovery
  4. Modern HTS and Assay Development: Views from the Front Line
  5. High Throughput Molecular Biology
  6. Signalling Pathways: Receptors and Enzymes
  7. Drug discovery Automation
  8. Diseases in the Developing World

We invite all members of the drug discovery community to attend the Drug Discovery meeting in 2010.

 

 

POSTERS

LA_2011_Logo_low

SLAS (Society for Laboratory Automation and Screening), are Sponsoring the 'Young Scientists Poster Award' at Drug Discovery 2010.

Present a Poster at the show and have the opportunity of winning the prestigious YSP Award. 

Win $500 + a Trip to Palm Springs to present your Poster at ALA Lab Automation 2011 + a chance to publish your work in JALA 

To Submit a Poster please send it to This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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The Speaker Programme is below.   If you have any questions about this please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it

To apply for a stand at the Innovation Zone contact:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it

To Exhibit click the link below, here you will be able to see the floorplan and book a stand.

 

sbslogo

SBS SHORT COURSES:   Tuesday 31st August

Course 1
Cell Culture and Fermentation Methods

Chair: Katy Gearing (GlaxoSmithkline)     


Course 2

Introduction to High Content Screening

Chair: Achim von Leoprechting (PerkinElmer)    


Course 3

Introduction to in vitro ADME Screening

Chair: Alison Wilby (AstraZeneca)     

Places are limited.  For Information and Booking please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it  

10.30 - -6.00pm on Tuesday 31st August.           
 

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Lonza_Logo
Lonza lunchtime tutorials
The Jaguar Suite, Ricoh centre - ground floor
September 1
12.50 - 1.25  -     Primary Sensors: Cell-Based Assays in Primary Cells -          Anthony Pitt
1.30 - 2.05 -       Achieving consistent, high volume primary cell supply -            Alex Batchelor
2.10 - 2.45 -       High throughput Nucleofection® in automated environments -    Dr. Gerhard Muster
  
September 2
 
12.35 - 1.15 -     High-content Analysis of Signaling Networks Enable Predictive Compound Profiling -    Anthony Pitt
1.20 - 2.00 -       Biomarker Discovery -             Dr. Swati Bhattacharyya, Ph.D.
 
 
The tutorials will be held in the Jaguar Suite, ground floor Ricoh centre, across the lobby from the exhibition area (follow the signs).
   Places are FREE - but are limited.   To secure your place pre-register now at www.lonza.com/elrig-dd2010


 

GOLD SPONSOR

Tecan

 

 

SESSION SPONSORS

chantestcblogo
PD_innovators

 

 

MEDIA SPONSORS

DDW_logo GLJ_logo_small ELA

 

 


 

2010 ELRIG/SBS/BPS   CONFERENCE PROGRAMME  -  RICOH ARENA

1st – 2nd September 2010

 

DAY 1 - 1ST SEPTEMBER 2010


Ion Channel Drug Discovery Strategies to Reduce Candidate Attrition Cells and Proteins for Drug Discovery Modern HTS and Assay Development: views from the front line
SPONSORS ChanTest and Cambridge Bioscience  Pharma Diagnostics   TTP LABTECH
Session Chairs

9.00 – 9.15

Martin Gosling, Novartis

Del Trezise, Essen BioScience

Russell Mortishire-Smith, J & J

Alan Watt, Cellzome UK

Katy Gearing, GSK

Tom Crabbe, UCB

Richard Eglen, PerkinElmer

Lorenz Mayr, Novartis

9.15 - 10.00

TRPA1-antagonists: the next morphine without the side-effects?

Neil Hayward, Hydra

Brains and Good Science – no substitutes

Colin Dollery, GSK

Cell Culture Technology ―  Past, Present, and Future

Ian Freshney, Glasgow Uni

Public-Private partnerships: Opportunities for collaborative research in Drug Discovery and the Medical Research Council Technology Group’s activities.

David Tapolczay, MRCT

10.00 - 10.30

Steve Goldstein, Chicago

Colin Dollery, GSK

Derivation & Utility of Cardiomyocytes from Human Pluripotent Stem Cells  


Chris Denning, Nottingham Uni

Application of HTS technology to discover small molecules that can reprogram somatic cells to iPS cells.

Kelvin Lam, Harvard, USA

10.30 - 11.15

COFFEE  

11.15 - 11.45
TBC

 

Biomarkers to aid target selection, candidate identification and clinical POC design

Chas Bountra, SGC Oxford

Hi-Spots - Functional micro tissues engineered in-vitro from stem cells and primary material for predicting in-vivo efficacy and toxicity

Prof Lars Sundstrom, Cardiff University

Screening and Characterisation of Nanobodies:  Where the small molecules meet Biopharmaceuticals

Sandra Turconi, Ablynx

11.45 - 12.15

Charles Large, GSK

Is More Better - Is all Data the Same?

Tina GaryantesSanofi-Aventis

Targeted Quantification of Cell Signalling (TIQUAS): A novel phosphoproteomics approach for biomarker discovery and drug profiling.

Neil Tobett, Activiomics

The use of SPR based methods for fragment based approaches in Drug Discovery

Walter Huber, F.Hoffmann-La Roche

12.15 - 12.45 Snapshots: BioFocus, Molecular Devices, Nanion, ChanTest Snapshots: Gentronix, Pharma Diagnostics, BioTek Snapshots: CCS , Cellectis Snapshots: PRS, TTP Labtech, CisBio, Axxam, Fortebio, BMG Labtech
12.45 - 2.45

LUNCH, POSTERS & Exhibition   

  

2.45 - 3.15

David Cronk, BioFocus

Attrition Reduction in Drug Discovery

Alan Watt, Cellzome UK

 

The production of soluble protein for assay as a metaphor for the decline of  big pharma

 Ceri Lewis, GSK

 

Biophysical Methods in the Lead Discovery Process: Combination is Key

Matthias Frech, Merck Serono

3.15 - 3.45
 
 

Can Fragment-Based Drug Discovery Impact Attrition ?

John Barker, Evotec

Antibodies, antibody fragments and alternate binding domains in drug discovery

David Humphreys, UCB

 The role that High Throughput Screening plays in Drug Discovery at GSK

Maite de los Frailes, GSK

3.45 - 4.15

Marianthi Papakosta, Pfizer

Physicochemical Properties and Drug Attrition

Paul Leeson, AZ

 

SBDD and Biophysical Screening using stabilised GPCRs

Ben Tehan, Heptares

Enhancing Hit Finding, Hit Validation and Lead Optimisation by Modern Compound Profiling 

Lorenz Mayr, Novartis

4.15 - 5.15

POSTER  PRESENTATIONS    


5.15 - 7.15

7.00 - 10.30

DRINKS RECEPTION

    'Band and Bites'  -  Sponsored by High Res BioSolutions  -  Band and Food in Sky Creations Lounge

 

DAY 2 - 2ND SEPTEMBER 2010


High Throughput Molecular Biology Signalling Pathways:  Receptors and Enzymes Drug Discovery Automation Diseases in the Developing World
SPONSORS Beckman Coulter   Caliper Life Sciences  
Session Chairs

9.00 - 9.15

Isro Gloger, GSK

Ray Owens, MRC OPPF

Steve Hill, Nottingham University

Tim Hammonds, CRT

Ulrich Schopfer, Novartis

Andy Zaayenga, LRIG

Steve Ward, L/pool School of Tropical Medicine

Paul Wyatt, DDU, Dundee University

9.15 - 10.00 Experience of Sanger’s Large-Scale Production DNA Sequencing Facility

Harold Swerdlow, Wellcome Trust

Intervention in and lessons from AGC protein kinases

Peter Parker, CRUK

uHTCS:  ‘In Situ’ Chemistry Methodology enabled by Labcyte's ADE Technology for Ultra High-Throughput Chemical Synthesis

Thomas Baiga, Salk Institute

TBC

10.00 - 10.30

Identifying potential new indications for assets using existing data and systems biology thinking.  
Chris Larminie, GSK

Tumour cell responses to the MEK1/2 inhibitor Selumetinib (AZD6244); what can modelling acquired resistance tell us?

 Simon Cook, Babraham Institute

The microfluidic toolbox – merging lab-on-a-chip technologies with lab automation for drug discovery

Holger Becker, Germany

Lead Optimization of Novel Boron-Containing Small Molecules for the Treatment of Human African Trypanosomiasis

Bob Jacobs, Scynexis

10.30 - 11.00

COFFEE BREAK

    

11.00 - 11.30 Unravelling cellular small molecule-protein interactions by chemical proteomics

Kalus Schneider, GSK

Targeting tumour metabolism: new drug discovery challenges

 

Susan Critchlow, AZ

 

A High Throughput Approach for Global Infectious Disease Surveillance –- The High Throughput Laboratory Network (HTLN) 

Chris Detter, LANL/UCLA

Phenotypic classification of compounds that block the proliferation of P. Falciparum in the blood stages

Kip Guy, St Judes Hospital

11.30 - 12.00

High-throughput protein production and crystallization for structural proteomics

Louise Bird,  OPPF, UK

 

Detection and characterisation of  sub-cellular cAMP signals

Debbie Willoughby, Cambs Uni

Rapid chemogenomlough by, Cambs Uniic analysis of the HDAC protein family using high throughput profiling

Sergei Romanov, Nanosyn

Whole cell HTS as a route to new antimalarials

Ian Bathurst, Medicines for Malaria Venture

12.00 - 12.30 Snapshots: STFC, Oxford Expression, Beckman Coulter, Eppendorf, Exetek Snapshots: Discoverx, Essen BioScience, Perkin Elmer Snapshots: Caliper Life Sciences, RTS, BioTek Snapshots:

12.30 - 2.00

LUNCH, POSTERS & Exhibition    


2.00 - 2.30

Next generation PCR diagnostics

Ian George, EMIGMA

 

Label-free live-cell imaging of GPCR function using dynamic mass redistribution (DMR) technology: exploiting pathway inhibitors to dissect complex optical response profiles

Evi Kostenis, Bonn Uni

Microwell Cell Arrays for High-Content Screening 

Holger Erfle, Bioquant

Novel therapeutic approaches against obligate intracellular pathogens using approved drug and natural compound libraries

Ralf Altmeyer, Pasteur Inst. Shanghai, China

2.30 - 3.00

Genome-wide mutagenesis and systematic phenotyping in the mouse

Prof Roger Cox, MRC

Combining multiple approaches to address 7-TM hit discovery

Rochdi Bouhelal, Novartis

The Sheffield RNAi Screening Facility- Building a functional service

Stephen Brown, Sheffield Uni

 Screens and infectious diseases: hunting for magic bullets, millions of compounds at a time

John Joslin, GNF, Novartis, US

3.00 - 3.30

COFFEE  BREAK 


3.30 - 4.45

Closing Debate:  'Challenges Facing Drug Discovery'

Will the Pharmaceutical Industry be more open for innovation?

Jackie Hunter, Pharmivation

New Directions in Drug Discovery

Jim Hagan, GMEC

 
5.15 - 7.15

Close of Conference

Prize Draw

Adrian Kinkaid and Steve  Rees

     
         

 


HOTEL BOOKING

To book a Hotel room in the Coventry Area go to the link below :

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Click here to book your drug discovery 2010 accomodation now

 



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