ELRIG Networking event: “PROTACs – An exciting therapeutic modality” – Download the event flyer here
Wednesday 6th December 2017 – 14:00 – 19:00
Alderley Park Conference Centre
Alderley Park, Nether Alderley, Macclesfield, Cheshire, SK10 4TG
Proteolysis targeting chimeras (PROTACs) offer a novel alternative to traditional small molecules. They inhibit proteins by binding to their functional regions and by recruiting E3 ligases to target the protein for degradation through the cells natural ubiquitin/proteasome pathway.
This event will focus on the recent developments in the field, provide an opportunity to learn about the types of protein complexes that are being considered as PROTAC targets and provide an introduction to those new to the field who are looking to start engaging with PROTACs within their own research. Informal presentations will be given by guest speakers followed by a networking session over food and drinks.
Confirmed Speakers & Presentation Titles
“PROTACs – Foundation and recent developments”
Thomas Hayhow (Medicinal Chemist, AstraZeneca)
“Understanding the role of class-I HDAC complexes: a precise method of targeting deacetylase activity in cells”
Shaun Cowley (Chair of Molecular Biology, University of Leicester)
“Small Molecule Designer Libraries for Mutant p53 Rescue”
John Spencer (Professor of Bio-organic Chemistry, University of Sussex)
An integrated chemistry and assay platform enabling client ubiquitin-system targeted drug discovery and towards supporting the development of PROTAC-based therapeutics
Jason Brown (Scientific Director, Ubiquigent)
“Bio-Techne as a partner for the discovery and development of PROTACs”
Robert Felix (Head of Product Management, Tocris)
“A toolkit for PROTAC characterisation and monitoring the pathway to degradation”
Craig Malcolm (Promega)
To register for the event, please click on the button to complete the registration form. We look forward to seeing you on the 6th December.
To download the pdfs on how to get to Alderley Park and the venue itself, please click on the links below.
Good to know
A good to know alternative for trains to the venue is Wilmslow train station, which is on a direct train line from London and Birmingham. This can be easier to get to on the train than Alderley Edge station and is only a 10 minute taxi journey to the site from the station.
Register for ELRIG's next networking event
Please click on the button and complete the short registration from for this networking event.
Please visit this page again in December for details of ELRIG 2018 Networking Events.