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Research & Innovation 2019

Editing the genome of human iPSCs using CRISPR/Cas9:Disease modelling and beyond…
Andrew Bassett (Wellcome Sanger Institute)

Artificial Intelligence in Drug Design
Ola Engkvist (AstraZeneca)

How do we drive the evolution and implementation of novel in vitro techniques in partnership with in vivo, ex vivo and in silico siblings?
Mark Holbrook (Certara)

Bioelectronics – is the next novel therapy class an electronic implant?
Jason Witherington (Galvani Bioelectronics)

CRISPR in Drug Discovery 2019

Genome Editing of Hematopoietic Stem Cells to Treat Genetic Diseases
Dr Matthew Porteus (Stanford University)

High efficiency genome editing using a novel mutant AsCas12a
Dr Mark Behlke (Integrated DNA Technologies)

Drug Discovery 2018

Day 1

How the chemical design and synthesis of linkers used in antibody drug conjugates drives the success of ADC drug development
Mark Frigerio (Abzena)

Drug Discovery: Reductionism v Complexity
Steven Zimmer (MitoDys and EpiCombi Therapeutics)

Combination Chemotherapy to Combat Antimicrobial Resistance
Professor William Hope (University of Liverpool)

Biomicrofabrication of Cellular Interfaces and Models
Dr Cristina Bertulli (University of Cambridge)

Potential for delta opioid receptor agonists as analgesics in chronic pain therapy
David Kendall (PharmNovo AB/UK)

Day 2

Medicines Discovery Catapult: a new model for collaborative R&D
Graeme Wilkinson (Medicines Discovery Catapult)

Building BRIDGEs: An Academic-Industry exercise
Mark Slack (Evotec)

Smarter IDO inhibitor profiling using biophysical, biochemical and cellular target engagement approaches
Dr Scott Pollack (Sygnature Discovery)

Fluorescence assay technologies for hit discovery
Helena Lindmark (AstraZeneca)

Discovery Technologies 2018

From One to Ten – Building Single and Interconnected Microphysiological Systems
Dr David Hughes (CTO, CN Bio)

In vitro-in vivo extrapolation from organ on a chip systems
Iain Gardener (Certara)

The union of organs-on-chips and mass spectrometric multi-omics: a technological convergence that will advance drug discovery
John Wikswo (Vanderbilt University)

Research & Innovation 2018

AI-Based Assessment of Cognitive Impairment in Neurodegenerative Diseases
Seyed Mahdi Khaligh Razavi (Cognetivity)

Robotics & Automation 2018

Modernising Pharma R&D. Why, What and How
Laura Williams (GlaxoSmithKline)

Some economic aspects of robotics and automation for the laboratory
Patrick Courtney (tec-connection)

What could be driving the Lab of the future and is the ‘Smart Lab’ really a thing?
Paul Kendall (FESTO)

Drug Discovery 2017

Using the Medicinal Chemistry Toolkit app supporting good translational science in projects
Andy Davis AstraZeneca)

The convergence of artificial intelligence and chemistry for drug discovery
Clive Green (AstraZeneca)

The value of Binding Kinetics in Drug Action
David Swinney (iRND3)

Big Pharma – Can We Fix It?
Nessa Carey (Carey International Impact Training)

Optimizing Binding Kinetics in Medicinal Chemistry: facts or fantasy?
Gerhard Müller (Gotham Therapeutics)

Using human genetics to make new medicines
Maya Ghoussaini (Open targets, Wellcome Trust Sanger Institute)

PKTool; a software tool to help decision making in early drug discovery
Neil Benson (Certara QSP)

Physiologically-Based Pharmacokinetics (PBPK) to Bridge between
In Vitro Discovery and In Vivo Human Studies
Amin Rostami (University of Manchester)

Tooling up to tackle cell wall biosynthesis
Chris Dowson (University of Warwick)

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