Discover the future of medicine with Prof. Ijeoma Uchegbu, Chair in Pharmaceutical Nanoscience at University College London and President-elect of Wolfson College, Cambridge. Learn about her groundbreaking research focused on why medicines work for some but not others, and how improving drug delivery can enhance efficacy and reduce side effects. Explore how Ijeoma’s team uses nanoparticles, 1/100th the width of a human hair, to improve drug delivery and alternative routes of administration.
We’re delighted to be partnering with thought leaders such as AZo Network & SelectScience as well as industry leaders to bring you the latest discoveries on our social media platforms and in our newsletters!
We’re sharing expert insights to advance breakthroughs in Drug Discovery with exclusive interviews and cutting-edge news from the community.
Dive into the latest breakthroughs and get insights from industry leaders.
Exclusive articles & videos from our partners.
Maria Ramos Zapatero Insights on Patient-Derived Organoids
Maria Ramos Zapatero, a postdoctoral fellow at the Bodenmiller Lab at ETH Zurich, who presented her work on stromal regulation of patient-derived organoid drug responses at ELRIG’s Drug Discovery 2023. Alicia Overall delves into Maria’s career. Exploring her research journey, from her PhD to her current postdoctoral position, and her thoughts on the future of science, including the importance of collaboration and data analysis.
Zahra Jawad’s Journey to Becoming a CEO and Founding Creasallis
Zahra Jawad is the founder and CEO of Creasallis, a company focused on antibody remodeling to improve penetration and treatment of solid tumours. Zahra introduced the company and their revolutionary work in her talk, ‘Creating enhanced biotherapeutics for oncology: The drug discovery perspective’, at ELRIG Drug Discovery Liverpool 2023. Alicia Overall sat down with Zahra and discussed her time at Drug Discovery 2023, career, work, advice, and everything in between.
How does your genetics affect your weight and can drugs help?
Are the new class of GLP1 anti-obesity medications a panacea?
GLP1R agonists, including semaglutide (Ozempic) and tirzepatide (Mounjaro) are hugely effective in the treatment of obesity. Originally developed for Type 2 diabetes, these drugs also cause dramatic weight loss. But how do they work, and are these therapeutics the long sought after solution to obesity? Here I will explore the history of these drugs, explain their mechanisms of action, and discuss their importance as a therapeutic for obesity, type 2 diabetes, and heart disease, and crucially, whether or not they are safe in the long term.
Biophysical sensors in studies on pharmacologically-dark G protein-coupled receptors
Pawel will discuss the latest developments that have enabled us to obtain deeper insights into ligand-receptor interactions, receptor conformational changes, receptor-transducer interaction and receptor-mediated signaling of class F GPCRs. These methodologies and knowledge are fundamental to enlarge pharmacological toolbox for these proteins as well could be applicable to other understudied receptors e.g. orphan GPCRs.
Emerging Technologies for Sustainable Pharmaceutical & Medical Devices Manufacturing
One of the biggest challenges in developing drugs for neurological disorders is that the majority of models available are non-human and just do not work the same way as human brains, therefore when trying to understand the mechanism of action, efficacy, off-target effects and toxicity, these models have significant limitations.
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